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As we get closer to an important data readout from our COVID vaccine program, I wanted to speak directly to the billions of people, millions of businesses and hundreds of governments around the world that are investing their hopes in a safe and effective COVID vaccine to overcome this pandemic. There are three key areas where, as with all vaccines, we must demonstrate success Adult want casual sex Clarkia Idaho order to seek approval for public use.

First, the vaccine must be proven effective, meaning it can help prevent COVID disease in at least a majority of vaccinated patients. Second and equally important, the vaccine must be proven safe, with robust safety data generated from thousands of patients.

And finally, we must demonstrate that the vaccine can be consistently manufactured at the highest quality standards. To ensure public trust and clear up a great deal of confusion, I believe it is essential for the public to understand our estimated timelines for each of these three areas. This means we may know whether or not our vaccine is effective by the end of October.

To do so, we must accumulate a certain of COVID cases in our trial to compare the effectiveness of the vaccine in vaccinated individuals to those who received a placebo. Since we must wait for a certain of cases to occur, this data may come earlier or later based on changes in the infection rates.

As Pfizer is blinded to who received the vaccine versus the placebo, a committee of independent scientists will review the complete data and they will inform us if the vaccine is effective or not based on predetermined criteria at key interim analysis points throughout the trial. Pfizer will continue running the trial through its final analysis point even if it is declared effective at an Women to fuck Antelope Valley-Crestview stage.

In the spirit of candor, we will share any conclusive readout positive or negative with the public as soon as practical, usually a few days after the independent scientists notify us. The second requirement is to prove that the vaccine is safe.

Our internal standards for vaccine safety and those required by regulators are set high. In the instance of Emergency Use Authorization in the U. Based on our current trial enrollment and dosing Sexy women in Portland Maine, we estimate we will reach this milestone in the third week of November.

Safety is, and will remain, our one priority, and we will continue monitoring and reporting safety data for all trial participants for two years. And finally, if we achieve a positive efficacy readout and a robust safety profile, the last requirement will be the Lust for sex Jefferson Oregon of manufacturing data that demonstrates the quality and consistency of the vaccine that will be produced.

Pfizer has been investing at risk since the early days of the pandemic to perfect our manufacturing processes and rapidly build up capacity. We expect to have our manufacturing data ready for submission before the safety milestone is reached. So let me be clear, assuming positive data, Pfizer will apply Sex dating in keo arkansas Emergency Authorization Use in the U.

All the data contained in our U. The timelines above reflect our best estimates of when these important milestones could be achieved.

For years Pfizer has been known for our high-quality standards. I cannot think of a breakthrough that would be Sexy girls or ladies near Ilminster meaningful to a greater of people than an effective and safe COVID vaccine. In the meantime, I hope you and your loved ones are staying safe and well. Related Hot Topics.

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